Increasing pleuromutilin activity of Clitopilus passeckerianus by chemical mutagenesis and improvement of production medium
Clitopilus passeckerianus NRRL 3100, which produces the antibiotic pleuromutilin, the precursor of the semi-synthetic Dynamutilin used solely for animal health, was mutagenized using 0.05, 0.10, 0.15, 0.20, 0.25, 0.30 and 0.35 mg mL-1 N-methyl-N'-nitro-N-nitrosoguanidine (NTG) in an attempt to...
| Published in: | Philippine Agricultural Scientist, The (Formerly the Philippine Agriculturist) Vol. 89, no. 1 (Mar. 2006), 20-33 |
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| Main Author: | |
| Other Authors: | , |
| Format: | Article |
| Language: | English |
| Published: |
2006
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| Subjects: |