Synthesis of single and tandem dna damages and mutagenesis studies of gamma-radiation-induced cross-linked guanine-thymine tandem lesion
The common environmental pollutant 1-nitropyrene and ionizing radiation are two examples of DNA damaging agents. Both these agents are mutagenic, tumorigenic, and carcinogenic. The reductive activation of the carcinogen 1-nitropyrene forms a C8 2'-deoxyguanosine adduct, N-(deoxyguanosin-8-yl)-1...
| Main Author: | |
|---|---|
| Format: | Electronic Resource |
| Language: | English |
| Published: |
Ann Arbor Michigan
ProQuest Information and Learning Company
[2007]
|
| Subjects: | |
| Online Access: | Full text access requires UP Webmail login |