Phosphodiesterases as drug targets
Cyclic nucleotide phosphodiesterases (PDEs) are promising targets for pharmacological intervention. Multiple PDE genes, isoform diversity, selective expression and compartmentation of the isoforms, and an array of conformations of PDE proteins are properties that challenge development of drugs that...
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Format: | Electronic Resource |
Language: | English |
Published: |
Heidelberg, New York
Springer
c2011.
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Series: | Handbook of Experimental Pharmacology
204 |
Subjects: | |
Online Access: | Available for University of the Philippines Diliman via SpringerLink. Click here to access |